What antibiotics are used for tonsil suppuration?
Tonsillitis (pyogenic tonsillitis) is a common bacterial infection caused primarily by group A beta-hemolytic Streptococcus (GAS). Patients often present with symptoms such as sore throat, fever, tonsil enlargement and purulent exudate. For this type of infection, rational selection of antibiotics is key. The following is a compilation of popular discussions and structured data on antibiotic treatment of tonsil suppuration in the past 10 days across the Internet.
1. Common pathogenic bacteria and preferred antibiotics

| Pathogenic bacteria | antibiotic of choice | alternative |
|---|---|---|
| Group A beta-hemolytic streptococci | Penicillin V potassium tablets | amoxicillin, cephalosporins |
| Staphylococcus aureus | Oxacillin | Clindamycin |
| Streptococcus pneumoniae | amoxicillin-clavulanic acid | ceftriaxone |
2. Comparison of antibiotic medication regimens
| Drug name | Usage and dosage | Course of treatment | Things to note |
|---|---|---|---|
| Penicillin V Potassium | 250-500mg/time, 3 times/day | 10 days | Skin test required |
| amoxicillin | 500mg/time, 3 times/day | 7-10 days | Penicillin allergy is contraindicated |
| Cefuroxime | 250mg/time, 2 times/day | 5-7 days | Take with food |
| Azithromycin | 500mg/day, once/day | 3 days | High resistance rate |
3. Recent hot topics of discussion
1.Penicillin resistance problem:The latest clinical data shows that the resistance rate of GAS to penicillin is still less than 5%, but attention should be paid to the sufficient duration of medication.
2.Controversy over short course therapy:Some studies support a 3-day regimen of azithromycin, but authoritative guidelines still recommend a 10-day course of penicillin.
3.Combined treatment with traditional Chinese medicine:The effect of Chinese patent medicines such as Pudilan Anti-inflammatory Oral Liquid in auxiliary treatment has aroused heated discussion.
4. Medication recommendations for special populations
| crowd | Recommended medicine | Taboo |
|---|---|---|
| pregnant woman | Penicillins | Avoid tetracyclines |
| children | amoxicillin granules | Quinolones are prohibited |
| Hepatic and renal insufficiency | ceftriaxone | Use macrolides with caution |
5. Analysis of common causes of treatment failure
1. Bacterial resistance (about 12% of cases)
2. Poor medication compliance (38% self-discontinued medication)
3. Co-infection with viruses (about 20% mixed infection)
4. Misdiagnosis (such as infectious mononucleosis)
6. Prevention and precautions
1. Diagnosis requires combined throat swab culture
2. Stay in bed during the fever period
3. It is recommended to consider tonsillectomy if the attack occurs more than 3 times a year.
4. During treatment, you need to drink enough water (2000ml/day)
Note: The above data are based on recent PubMed clinical research, updated guidelines from the Chinese Journal of Otolaryngology-Head and Neck Surgery, and consultation statistics from Internet medical platforms. Please follow your doctor’s instructions for specific medication. This article is for reference only.
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