Why is eczema so bad? ——Analysis of 10 hot questions and scientific responses
Eczema, a common skin inflammation, has recently sparked widespread discussion on social platforms and health forums. Many patients reported "recurrent attacks" and "no cure after long-term treatment", which has become one of the hotly discussed health topics on the Internet in the past 10 days. This article combines the latest medical research and hot discussions, and uses structured data to provide you with an in-depth analysis.
1. Top 5 most searched topics related to eczema on the Internet (data statistics period: last 10 days)

| Ranking | Hot search topics | Search volume (10,000) | Main discussion platform |
|---|---|---|---|
| 1 | Why does eczema get itchy the more you scratch it? | 28.5 | Weibo, Xiaohongshu |
| 2 | Reasons for recurring eczema in ten years | 19.2 | Zhihu, Baidu Tieba |
| 3 | Actual measurement of side effects of hormone ointments | 15.7 | Douyin, Bilibili |
| 4 | Controversy over probiotics treating eczema | 12.3 | WeChat public account |
| 5 | Misunderstandings about children’s eczema care | 9.8 | Mom Net, Baby Tree |
2. Five core reasons why eczema is difficult to heal (medical research data)
| Cause classification | Specific performance | Proportion | solution |
|---|---|---|---|
| Skin barrier defects | FLG gene mutation causes stratum corneum abnormalities | 43% | Ceramide skin care products |
| Immune system abnormalities | Th2 cell overactivation | 35% | biologic therapy |
| Environmental triggers persist | Dust mites/pollen/pet dander | 62% | Air purifier use |
| Treatment is not standardized | Self-discontinuation of hormone ointments | 78% | Step treatment according to doctor’s instructions |
| Psychological stress effects | Anxiety-itch vicious cycle | 51% | mindfulness stress reduction training |
3. Three major treatment controversies that have been hotly debated recently
1.Hormone phobia phenomenon:A large number of users on the short video platform shared their experiences of "hormone withdrawal", but dermatologists from tertiary hospitals pointed out that the rational use of weak-acting hormones is still the preferred option in the acute phase.
2.Microecological therapy controversy:A probiotic combination recommended by an Internet celebrity was recently exposed as lacking clinical evidence. Experts recommend choosing specific strains approved by the FDA (such as L. rhamnosus GG).
3.The craze for external treatment with traditional Chinese medicine:Taobao data shows that the weekly sales of Chinese eczema ointments increased by 240%, but some products were found to have illegally added Western medicine ingredients. We are reminded to choose formulas formulated by regular medical institutions.
4. Five practical issues that patients are most concerned about
| question | Key points of professional answers |
|---|---|
| Bath water temperature control | 32-34℃ (actual measurement is slightly lower than body temperature) |
| Moisturizer selection | Creams are better than lotions (more occlusive) |
| Clothing material | Tencel>Cotton>Wool (breathability test data) |
| Diet control | Only 30% of patients need to avoid foods (allergen testing is required to confirm) |
| Exercise advice | Rinse immediately after swimming (chloride ion irritation problem) |
5. Latest treatment progress (clinical data in 2023)
1.JAK inhibitors:Phase III clinical trials showed a 48-week remission rate of 68% (traditional therapy was 39%)
2.UV Therapy Upgrade:Targeted UVB device shortens treatment cycle to 4-6 weeks
3.Microbial transplantation:Healthy donor skin flora transplantation trial achieves phased results
Conclusion:Eczema treatment requires the establishment of a trinity plan of "repairing the barrier + controlling inflammation + avoiding triggers". Recently, the State Food and Drug Administration has accelerated the approval process of new topical PDE4 inhibitors, bringing new hope to patients with refractory eczema. It is recommended that patients obtain personalized treatment plans through a combination of "online consultation + offline follow-up".
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